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Advances in the Treatment of Acute Myeloid Leukemia: New Drugs and New Challenges

BTK is a critical component of the BCR pathway, and ibrutinib, a first-in-class, once-daily, oral covalent BTKi, was developed to impede BCR pathway activity

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Frontiers of Environmental Science & Engineering, 10(1), 168176

It helps reduce inflammation and irritation, accelerating the healing process of wounds, cuts, and other skin injuries

Compared with normal animals, Nrf2-deficient mice have more pronounced effects on lipopolysaccharide (LPS)-induced microglial activation and inflammatory response, with lower levels of IL-1, IL-6, IL-12, and TNF- in the brain ( Moreover, increasing evidence indicated that Nrf2 may regulate mitochondrial function and metabolism