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Using the Broad Institute's Connectivity Map (cMap), a database that profiles gene expression changes produced by thousands of bioactive molecules, Pickart and Vasquez-Soltero identified that GHK-Cu influences the expression of more than 4,000 human genes

This loss of translocase function was accompanied by increased externalization of PS, a key eat-me signal that flags cells for recognition and phagocytosis by macrophages

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1,4-Bipiperidine-1-carboxyclic acid, 3-hydroxy-8-apo-E-caroten-8-al, cyclo(L-Trp L-Pro), heptanal, 2-benzylidene-(E), leucine proline dipeptide, meconin, and SHCHC (2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, precursor of vitamin K) were detected only for anaerobically cultured bacteria (Supplementary Table S4)

By combining tumour transcriptome and metabolome analyses, we aimed to validate the role and mechanisms of potential diagnostic biomarkers in lung cancer, thereby enhancing the reliability of our results

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