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2014, doi:10.1111/acel.12269 Elshorbagy AK, Valdivia-Garcia M, Refsum H, Smith AD, Mattocks DA, Perrone CE: Sulfur amino acids in methionine-restricted rats: hyperhomocysteinemia

Studies indicate that its hepatotoxicity is closely associated with metabolic dysregulation, endoplasmic reticulum stress, and mitochondrial dysfunction

To confirm localization of EPRS1 to Rab5-positive vesicles, we used an activation-mimic form of Rab5(Q79L)-CFP along with EPRS1-YFP and then stained activated AKT with anti-AKT Ser473 antibody to trace their location to the early endosomal membrane upon LPS stimulation (Fig

RAGE was first described as a receptor for advanced glycation end products (AGEs)

The effect remains gradual and cumulative rather than instant

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