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IC 50 values were determined by three parameters non-linear regression [inhibitor conc

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A detailed overview of these aspects could encourage further research and provide new insights into impeding the development of hair greying

\n\n\n\n It is critical to note, however, that preclinical safety data no matter how consistently positive cannot be directly extrapolated to humans without proper clinical trials

Methods: Thirty- three male Sprague Dawley rats were divided into 3 groups (n=11 per group)

The observed differences appear to be dependent on the animal model, as previous studies have shown that MitoQ is well tolerated at concentrations up to 500 M in drinking water over several weeks, without causing adverse effects on behavior or metabolism (57, 83)