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New strategies aim to minimize harm

Khaleghi S, Ju JM, Lamba A, Murray JA (2016) The potential utility of tight junction regulation in celiac disease: focus on larazotide acetate

Effects depend on peptide class, dose, delivery route, and baseline health

doi: 10.1152/ajpheart.00022.2014 110

Safety Profile and Adverse Event Data Clinical trial safety data for retatrutide is broadly consistent with what has been reported for GLP-1 and GIP/GLP-1 classes, with a few nuances driven by the addition of glucagon receptor activity