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In human colon cancer cells, silencing NNMT resulted in approximately a 30% increase in NAD + levels (Xie et al., 2014), whereas NNMT overexpression decreased NAD + levels by 30% (Xie et al., 2014)

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Alpha diversity (Observed, Shannon, phylogenetic diversity (PD)) and beta diversity (weighted and unweighted UniFrac) indices were analyzed with rarefied samples (ileum at 21,497, cecum at 34,012, and colon at 7435 reads) in C3H/HeOuJ mice

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Adding NA to pro-inflammatory M1 macrophages increased their efferocytosis and shifted their metabolism toward a more oxidative, M2-like state

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