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For instance, differences in age, education, and geographic location have all been shown to affect nicotine use (4), and thus, the reported findings may be interdependent on other sociodemographic or developmental factors

Supporters of the bills noted that tobacco use remains the leading cause of preventable death in the U.S., with as many as 34,000 Californians dying each year

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As a direct consequence of a reduction in exposure to carcinogenic toxicants, switching to a cMRTP use should also lead to a significant reduction in urinary genotoxicity (a biomarker of total genotoxic exposure) compared with continued smoking and approach the urinary genotoxicity observed upon smoking abstinence [37]

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