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If your goal with NAD+ is cellular energy and recovery, then pairing the protocol with heavy drinking is sending opposing signals to the same system: you are supplementing a coenzyme while simultaneously running it down

Nucleic Acids Res 38 , e149 (2010)

Prediction of STN-DBS for Parkinsons disease by uric acid-related brain function connectivity: a machine learning study based on resting state function MRI