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We observed that a fiber-type shift and lower mitochondrial respiration are associated with reduced exercise capacity in patients, but these do not necessarily contribute to the pathophysiology of post-exertional malaise, as fiber-type shifts occur at a very slow pace and could have been present before long COVID

This suggests that perioperative administration may optimise haemodynamic stability, particularly in patients with pre-existing compromised cardiac function

Schauer, J

In this study, treatment with ALC was initiated at birth in an attempt to rescue abnormalities in brain pathology including defects in dendritic arborization that are established during the first weeks of life [49], [73]

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