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In the Phase 2 study the highest arm continued upward toward higher maintenance targets, but the core principle held throughout: escalate only after the current step is tolerated , in roughly four-week increments

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Amylin and GLP-1 are two different hormones that both reduce appetite but through different brain pathways

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Note: As of January 2023, Modifier JZ was introduced to attest that there was zero drug wastage, and at least one of these modifiers (JW or JZ) is now required on all applicable Medicare drug claims

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