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10.1096/fj.202201202RR 120 LinW.ZhangQ.LiuL.YinS.LiuZ.CaoW

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Many patients who have undergone cyclophosphamide treatment present with severe hemorrhagic cystitis

First, viral engagement with angiotensin-converting enzyme 2 (ACE2) impairs the conversion of angiotensin II (Ang II) to angiotensin 17 (Ang 17), thereby favoring Ang II accumulation and enhanced generation of superoxide anion (O)

Study Design: A literature review analyzing mechanisms, clinical applications, and limitations of natural products in nasal delivery

For meaningful interpretation, this requires the reference metabolite (i.e., the ratio denominator) to be stable