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Centella asiatica enhances memory function without altering locomotor activity in the Y-maze test To examine the effects of CAE on scopolamine-induced cognitive impairment, a series of Y-maze behavioral tests was performed

Chem Biodivers 9:10451054

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Integrative omics analyses reveal that MYC orchestrates ammonium metabolism reprogramming in prostate cancer through direct transcriptional control of GLS, with TCGA-PRAD data confirming co-amplification of MYC and GLS (q 20 mM) impair immune cell function by competitively inhibiting monocarboxylate transporters (MCTs), MCT1 in T cells and MCT4 in NK cells, leading to metabolic paralysis or apoptosis (180) ( Figure 4 )

A phase Ib clinical trial NCT03528642 examined CB-839/telaglenastat safety and anti-tumor activity in combination with radiation therapy and temozolomide in patients with IDH-mutated diffuse or anaplastic astrocytoma

They may help improve mood, focus, and hyperactivity, supporting children with autism in managing some behavioral challenges and enhancing cognitive abilities