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doi: 10.1016/j.rdc.2022.02.010 4

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[Google Scholar] 72.Loguercio C, Piscopo P, Guerriero C, Girolamo VD, Disalvo D, del Vecchio Blanco C

GPX4 in cell death, autophagy, and disease

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Pyruvate is a metabolic product immediately downstream of enolase and has been successfully and safely used in humans as a clinical antioxidant, including as a cardio- and neuro-protectant ( Figure 3C )