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Amico-Roxas M, Caruso A, Cutuli VM, et al

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As weve noted before, the function is dependent on structure, and the string of amino acids must fold into a specific 3-D shape, or conformation, in order to make a functional protein

[Low et al 2007 1] [18] Function [edit] The activity of GSTs is dependent upon a steady supply of GSH from the synthetic enzymes gamma-glutamylcysteine synthetase and glutathione synthetase, as well as the action of specific transporters to remove conjugates of GSH from the cell

We examined the protein and mRNA levels of Nrf2/HO-1 and the activities of downstream antioxidant enzymes in GCs to elucidate the underlying mechanisms