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Digging the intercellular crosstalk via extracellular vesicles: may exosomes be the drug delivery solution for target glioblastoma

However, excessive production or metabolic imbalance of these highly reactive and unstable free radicals can lead to oxidative stress (OS)

doi: 10.1038/mt.2016.159 124 WangQRenYMuJEgilmezNKZhuangXDengZet al

Ginsenoside Rb1 alleviates alcohol-induced liver injury by inhibiting steatosis, oxidative stress, and inflammation

The two human 3-hydroxysteroid dehydrogenases have been investigated in detail by Thomas and coworkers (e.g., Thomas et al., 2005), and their studies indicate that the 3-ketosteroid 5-AD formed by oxidation of dehydroepiandrosterone with NAD + as a coenzyme remains as an intermediate bound to the enzyme prior to its isomerization to 4-AD

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