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As a result, the inhibition of E2F by pRB is reduced, which enables the initial transcription of E2F-dependent genes, including cyclin E and other cell cycle genes

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Puohiniemi R, Butcher S, Tarkka E, Sarvas M (1991) High level production of Escherichia coli outer membrane proteins OmpA and OmpF intracellularly in Bacillus subtilis