ShimbaACuiGTani-ichiSOgawaMAbeSOkazakiFet al
eNeuro 10: 406-423
Tetramers loaded with SARS-CoV-2 peptides can bind to T cell receptors that recognize those peptides
This is beneficial for resistance to reinfection by the same or different pathogens, including parasites (110)
Spatial hubs for crosstalk: contacts and microdomains Organelle contact sites are active hubs where multiple reactive chemistries are choreographed rather than isolated: at mitochondriaER contacts (MAMs), tightly coupled Ca and lipid transfer is synchronized with ROS generation and detoxification, so that ONOO , H 2 O 2 and RSS can be relayed across adjacent membranes via redox relays and peroxiporins, shaping metabolism, unfolded-protein responses and cell-death thresholds, at mitochondrialysosome and peroxisomemitochondria interfaces, fatty-acid flux, the labile iron pool (LIP) and ROS/RSS hand-offs are co-regulatedperoxisomal -oxidation and catalase buffering, lysosomal iron mobilization and mitochondrial electron transport together set the likelihood of Fenton chemistry and lipid peroxidation (DiGiovanni et al
The co-treatment with oil-soluble extract of onion in these rats ameliorated effects of aflatoxin on serum biochemical biomarkers