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465 The downregulation of GLP-1R expression may represent a significant contributory factor to the co-occurrence of hypertension and hyperglycemia

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Elevated glutathione levels add a third recovery dimension by neutralizing the oxidative stress that accumulates in muscle tissue during exercise

Patients with Duchenne muscular dystrophy have a higher incidence of neurodevelopmental disorders, particularly autism spectrum and attention-deficit/hyperactivity disorders, than the general population.

Recent studies have demonstrated that administration of an ALDH2 activator Alda-1 (N-[C1,3-benzodioxol-5-ylmethyl]-2,6-dichlorobenzamide) protects rodents from tissue damage in chronic alcohol consumption-induced atrial fibrillation [22] and hepatic ischemia [23], through a reduction in accumulation of reactive aldehydes