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Reactive oxygen species (ROS), produced via GSH-mediated pathways, can serve as danger-associated molecular patterns, stimulating dendritic cells and promoting T-cell expansion [82]

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The SH-SY5Y human neuroblastoma cell lines exposed to 100 and 50 M AFB1 and FB1 mycotoxins for 24 h, manifested a significant increase in ROS formation, though the trace of endoplasmic reticulum stress was not observed (240)

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As cells further engage in recycling with reversed GPI, more labelled carbon can be released as 13 CO 2 when glucose enters oxPPP for the second or third round, thus resulting in labelling enrichment in lower glycolysis 0.6, which corresponds to near full oxPPP but with no cycling, as expected (Fig