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reported that under high hydrostatic pressure, downregulation of cystathionine lyase/hydrogen sulfide (CSE/H 2 S) induce ferroptosis thereby exacerbating VSMC dysfunction

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The strategy of wrapping extracellular vesicles can not only effectively protect proteins from the degradation of proteases in the blood and the phagocytosis of phagocytes, but also help to penetrate the barrier of the cell membrane (136)

Blood-brain barrier (BBB) is a semipermeable membrane barrier situated between the bloodstream and brain, with the role to regulate the influx and efflux of exogenous compounds and xenobiotics into the brain, or biological substances needed for brain metabolic activity and neuronal function [38]

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A., Oyewale, J