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The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial

She also earned a masters degree in 2004 from the University of Nebraska Medical Center

doi: 10.1016/j.mrfmmm.2004.06.056

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Volume of Distribution The apparent volume of distribution reflects a balance between binding to tissues, which decreases plasma concentration and makes the apparent volume larger, and binding to plasma proteins, which increases plasma concentration and makes the apparent volume smaller

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Lu P, Graham L, Wang Y, Wu D, Tuszynski M