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As riboflavin has a key role in the glutathione redox cycle, it has been expected that riboflavin status could affect redox status, and consequently, glutathione content and activity of antioxidant enzymes

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In nonneuronal tissues, experimental studies have demonstrated that melatonin inhibits NO production induced by lipopolysaccharide (LPS) that induce the activation of the immune response 77

A novel murine GITR ligand fusion protein induces antitumor activity as a monotherapy that is further enhanced in combination with an OX40 agonist