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Second, ERKO/Wnt-1 mice, which have no functional ER-, develop estrogen-induced mammary tumors23-25

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DeepDriver 35 used gene mutation types as features, constructed a K-nearest neighbor graph based on the Pearson correlation coefficient, and trained a convolutional neural network to identify cancer risk genes

The mitochondrial pyruvate carrier (MPC) regulates the entry of glycolytic pyruvate into the mitochondria, serving as a key node linking glycolysis to OXPHOS [51]

For soluble proteins , the supernatant was incubated with NiNTA beads (Thermo Fisher Scientific) while rotating at 4 C for 1 h