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J Hepatol (2020) 72(2):34252

Exploiting the epigenome to control cancer-promoting gene-expression programs

It inhibits the NRF2-Keap1 interaction, alleviating oxidative stress and inflammation

In vivo, LA can be reduced to dihydro LA (DH-LA) by dihydrolipoamide dehydrogenase [28]

Moreover, the gut microbiota plays a critical protective role by promoting mucus production in intestinal epithelial cells, thereby forming a barrier against pathogenic microorganisms and environmental toxins