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"The higher rates at which adolescent, women, and white smokers develop symptoms of nicotine dependence given the same quantity smoked daily seem to reflect differences in sensitivity to nicotine

For example, 45.6 percent of males aged 18 to 25 with AMI smoked in the past month, compared with 36.8 percent of males aged 18 to 25 without mental illness

This represents 70% of the worlds population

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Although school-based and community interventions with a control group should be designed as randomized studies 19 , allocating randomly to the experimental or control conditions is challenging to implement in practice