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Constant exposure can downregulate these receptors, requiring higher doses for the same effect

With the current absence of technologies to rectify the actual mutations that underlie mitochondrial diseases, medical science can only address the resulting oxidative stress as a potential therapeutic option

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Discovered in 2015 by researcher Changhan David Lee and colleagues at the University of Southern California, MOTS-c sits at the intersection of some of the most active areas in longevity science: mitochondrial biology, insulin sensitivity, skeletal muscle metabolism, and the molecular response to exercise

The compound's ability to support liver function also contributes to clearer skin, as a healthy liver is better able to process and eliminate toxins that might otherwise manifest as skin problems

SLU-PP-332 SLU-PP-332 is a novel small molecule and a potent pan-agonist of the estrogen-related receptors (ERR, ERR, and ERR), which are key regulators of energy metabolism and mitochondrial function