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Antimuscarinics for Overactive Bladder Oxybutynin Trade Name: Ditropan Drug Class: Muscarinic antagonist Mechanism of Action: Muscarinic antagonist that is selective for M1 & M3 vs M2 receptors Relaxes the urinary bladder, and produces a antispasmodic effect

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Further, we blocked GABBR1 using CGP35348, a specific competitive antagonist of the GABA B receptor

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