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These transmembrane proteins connect the internal cytoskeleton to the extracellular matrix, enabling cells to sense and respond to their environment

[DOI] [PMC free article] [PubMed] [Google Scholar] [85].Sharma A, Yuen D, Huet O, Pickering R, Stefanovic N, Bernatchez P, de Haan JB, Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium

Biomarker Context: When Oxidative Stress Assessment May Be Relevant Not all patients have elevated baseline oxidative stress, and not all benefit from antioxidant supplementation

When mitochondrial depolarization and proteasome-dependent rupture of the outer membrane occur, PHB2 binds the autophagosome membrane-associated protein LC3 via the LC3 interaction region structural domain (Fig

The presence of high levels of VEGF-C and tumor lymphangiogenesis is associated with immunosuppression but might also indicate better efficacy for ICB treatment

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