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NHS Treatment Schedule and Dosing for B12 Injections The NHS follows evidence-based protocols for B12 replacement therapy in pernicious anaemia, with treatment divided into two phases: loading (induction) and maintenance

In some cases, the side effect of night sweats may be preferable or the only option to treat your specific condition

Twice-daily dosing maintains stable tissue levels

Formulations outside these ranges are either underdosed (ineffective) or overdosed (wasteful and potentially hepatotoxic at methionine levels above 100 mg per injection)

The Three Stages of Menopause Stage 1: Perimenopause or Menopause Transition Perimenopause may start eight to 10 years before actual menopause

Here is a revised and more accurate explanation of the reasons a UK GP surgery might refuse to give a B12 injection a day earlier than scheduled, incorporating the points youve raised and providing a more scientifically grounded perspective: 1