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On one hand, targeting NFAT provides a clean, well-defined approach to reducing bone resorption

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In humans, the following genes generate different subclasses of antibodies: two alpha gene segments (IgA1 and IgA2), four gamma gene segments (IgG1, IgG2, IgG3 and IgG4), one mu segment (IgM), one epsilon segment (IgE) and one delta segment (IgD)