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Seo J, Pao P-C, Kritskiy O, et al (2020) A cyclin-dependent kinase 5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes

[22] [23] GHK-Cu has been found to induce a systemic enhancement of healing in rats, mice, and pigs

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GHK is a naturally occurring bioactive amino that forms an ionic complex with copper in human plasma

1 Adverse reactions that occurred in 2% of patients treated with RADICAVA and 2% more frequently in placebo-treated patients 1 Hypersensitivity reactions and cases of anaphylaxis have been reported in postmarketing reports with RADICAVA 1 Discontinuations were not associated with contusion, gait disturbance, or headache in patients treated with RADICAVA 2 No known drug interactions based on in vitro drug interaction studies 1 RADICAVA ORS Was Generally Well Tolerated 1,3 The safety profile of RADICAVA ORS was demonstrated in a 6-month, phase 3, open-label clinical trial in 185 patients

The short GHK-Cu half life leaves zero room for error