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For more details, see reference ( The final section will focus on the MM environment, with particular attention to the bone marrow (BM) niche, aiming to identify new players and leverage their unique properties to enhance tumor eradication

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When this enzyme shuts down, the methylation cycle stalls, leading to a vicious cycle where the body cannot produce the very antioxidants (like glutathione, which relies on downstream methylation pathways) needed to clear the viral-induced oxidative stress

Hcy interacts with cysteine-825 residues situated on the pro-insulin receptor within the endoplasmic reticulum (ER), thereby disrupting the formation of initial disulfide bonds