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Trisulfide bond-mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity

10.3168/jds.2010-3832 J Dairy Sci

By summarizing the components of ROS, the role of oxidative stress in gliomas pathogenesis, the effects of oxidative stress on targets such as Nrf2, NOX2, NOX4, DGAT1, PKM2, PTPN2, PHB, OSMR, and PAX6 are presented in this paper, and some phytochemicals shown to alter glioma cell growth by affecting oxidative stress are discussed