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doi: 10.1038/nrm2466

5 Conclusion and Perspectives Dysfunction of the tumor suppressor p53 has a widespread impact during carcinogenesis

In a micronucleus assay in mice, aspartame was administered as a single oral dose at 2501000 mg/kg bw by gavage, and bone marrow and peripheral blood samples were obtained at 24, 48, or 72 hours after dosing

Reconstitution of miR-4715-3p has been validated to be an essential method that hinders the process of tumorigenesis by inhibiting GPX4 and enhancing cisplatin sensitivity (Gomaa et al., 2019)

Samples were analyzed in triplicate using an Amplex Red kit (Amplex Red Hydrogen Peroxide/Peroxidase Assay Kit

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