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is the founder of Fragmatics and serves on the scientific advisory boards of Protai Bio, Infinitopes and Mobilion Systems

The cysteinylglycine formed in the transpeptidase reaction is split by dipeptidase (Reaction 6)

While trazodone is sometimes prescribed to help with sleep or anxiety, it does not have the same properties or risks as opioids, which are typically used for pain relief and have a high potential for addiction

While preclinical evidence suggests minimal toxicity at therapeutic doses, further studies are needed to assess potential hepatotoxicity, nephrotoxicity, and other organ-specific toxicities, especially at higher doses and over extended periods

This study underscores the utility of metabolomics in discovering endogenous anti-inflammatory regulators and provides a compelling rationale for developing carnosine-based interventions for the treatment of inflammatory lung diseases