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Indeed, HO-1 induction fosters the polarization of macrophages towards an anti-inflammatory M2-like profile and promotes a tolerogenic phenotype in DCs (83, 94), both reducing the activation of T cells and favoring the Treg differentiation, resulting in the suppression of autoreactive responses (47)

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The similarity between overlap in the pathophysiology of ME/CFS and FM was demonstrated by Schutzer et al

Finally, a summary would reveal a consistent demonstration of particular beneficial effects, i.e., the activation of collateral pathways related to the injurious occlusion (Vukojevic et al., 2018

Programming cells by multiplex genome engineering and accelerated evolution

248 Drp1 is a fission-promoting protein