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Figure 4 Alterations in the intracellular redox status are often associated with GSH depletion (Polonikov, 2020) and endogenous GSH deficiency, due either to decreased biosynthesis and/or increased consumption, is a marked contributor to the pathogenesis of numerous diseases via mechanisms including oxidative stress and inflammation

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In neonatal rat cardiomyocytes, mitochondrial p38 interacts with Mn Superoxide Dismutase, phosphorylating it at key residues, thereby reducing ROS and promoting survival, including in settings of 17-estradiolmediated protection [130, 138]

In fact, researchers are beginning to connect the dots between mold exposure and a variety of chronic health problems, coining the term Chronic Inflammatory Response Syndrome - or CIRS for short - to encompass any sort of health problem related to mold exposure

Kirkby, A.R.J

Note that genes with missing transcript IDs were filtered from the GTF file, which is a known issue with some GTF files (see DESeq2 v1.38.3 was used to perform differential gene expression analysis for 3- and 10-h samples separately 81