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Highdose IV protocols (5001,500 mg daily for ~10 days) have been used in openlabel studies for substance use disorder, with reports of reduced cravings and improved mood in followups [2] [9]

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Proc Natl Acad Sci U S A 108(1):373378 Zhang CF, Snell CR, Loh YP (1999) Identification of a novel prohormone sorting signal-binding site on carboxypeptidase E, a regulated secretory pathway-sorting receptor

After thinking long and hard about all the different components of our program at JE Dunnthe programs/events that we host, the community volunteering that we do, the internal work to break down barriers of entry, the collaboration with our talent acquisition and workforce teams to increase the diversity of our staffI believe the differentiator for our program is how we make it personal

However, the current evidence base is largely preclinical, and no large-scale human clinical trials have confirmed its efficacy