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Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy

Oncology (Williston Park) 36(10):600-603, 2022

Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al

Therefore, PDENs have been widely used to treat a variety of conditions (Yun et al., 2021), intestinal inflammatory disease (Yaz et al., 2021), and tumors ( GENs Molecular composition of GENs GENs derived from grapes, including proteins, lipids, RNA (mRNAs, miRNAs, and lncRNAs), and natural small molecular compounds, can be transferred to recipient cells and exert biological effects, acting as messengers in intercellular or cross-species communication to treat disease by regulating biological functions (Songwen et al., 2013)