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Additionally, the NPs showed antiapoptotic and antioxidant properties and effectively reduced inflammation (180)

NH2-triP is then transformed into 6-pyruvoyltetrahydrobiopterin (6-PTP) by 6-pyruvoyl tetrahydrobiopterin synthase (PTPS), and finally, 6-PTP is reduced to BH4 via three successive reactions catalyzed by sepiapterin reductase (SPR)