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SKU: 26300858805
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36 Another cause could be a defect in leptin signaling which is related to the suppressor of cytokine signaling 3 (SOCS3) and insulin receptor substrate/phosphatidylinositol 3-kinase (IRS/PI 3-K) signaling pathways

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Studies have shown that ROS fosters vascular injury by promoting phenotypic switching and apoptosis of VSMCs (78, 79), while the inhibition of ROS reverses this effect (80)