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Energy metabolism of follicular environment during oocyte growth and maturation

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The Notch signaling pathway can promote the activation of T cells, leading to cell proliferation, autophagy, cell recruitment, proteolysis, and inflammatory response

In this regard, pangamic acid has been a medication that stimulates cellular respiration for decades on the market throughout the world

Therapeutic strategies aiming at iron metabolism as a possible target in MDS and AML can be roughly distributed in four approaches: reduction of iron required for cellular functions via iron chelation, modulation of proteins involved in iron metabolism, induction of ferroptosis und exploitation of iron proteins for the delivery of antileukemic drugs ( Figure 3 )