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Generally, in low intracellular calcium, the autoinhibitory domain binds with the kinase domain of the CDPKs, hence, restricting the target protein phosphorylation activity of the CDPKs

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Excessive ROS production due to mitochondrial dysfunction contributes to NAFLD development, making the decrease in mitochondrial ROS production an emerging target to alleviate NAFLD

Notably, recent findings have highlighted six novel high-priority RA risk loci, including RPP14 (DNASE1L3-ABHD6-PXK), PXT1 (ETV7), MIR5708 (TPD52), DDX6 (CXCR5), SUOX (CDK2), and PCAT29 (LOC145837) [27]

The role of aryl hydrocarbon receptor agonists in the treatment of vitiligo Arch Dermatol Res doi: 10.1007/s00403-024-03405-2 Bitterman D, Wang JY, Collins A, Zafar K, Kabakova M, Patel P, Joerg L, Cohen M, Austin E, Jagdeo J