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BIO-65043) and gene expression was determined using RT-qPCR performed with a Roche LightCycler 480 system (Roche Diagnostics Corporation, Indianapolis, Indiana, USA) according to MIQE recommendations 57 as previously described 19

Curcumin-primed exosomes potently ameliorate cognitive function in AD mice by inhibiting hyperphosphorylation of the Tau protein through the AKT/GSK-3 pathway

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Current research protocols typically employ cycling approaches (4-8 weeks active, 2-6 weeks rest) rather than continuous long-term use