napqi and glutathione File:Acetaminophen metabolism.jpg Most people don't realise this

Most people don't realise this Paracetamol breaks down into a toxic compound called NAPQI. Your liver neutralizes it using glutathione (your body's defense shield). But when you take it too often Paracetamol metabolites. NAPQI: N acetyl p benzo quinone imine; UGT: Download Scientific Diagram Acetaminophen metabolism. NAPQI, N acetyl p benzoquinone imine; CYP450, Download Scientific Diagram SUPER EASY MEMORY Too much Tylenol More NAPQI Less glutathione Liver dies NAC More glutathione Liver saved A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 One question. One concept. One point on exam day. Acetaminophen overdose? You should recognize the antidote in seconds, not after rereading a textbook. Train your brain with active recall and build

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