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2023;34(Suppl 2):S10612

These concepts, outlined in Figure 1, are relevant for our discussion

In vitro experiments using a Bcl-2 inhibitor and adeno-associated virus (AAV)-mediated Bcl-2 knockdown confirmed that the protective effects of MOTS-c against NASH-induced mitochondrial dysfunction, inflammation, and fibrosis are dependent on Bcl-2 function

AAV-mediated gene therapy for AIP utilizing recombinant AAV8-based serotype vector encoding murine HMBS (rAAV2/8- HMBS ) under the liver-specific transcriptional control of a hepatocyte enhancer and promoter has been tested in mice with AIP

The markets that are very big for IPOs tend to be hot markets for SPACs. Nevertheless, an online poll conducted by Deloitte during a December webcast and released Tuesday found some signs of caution, with 47% of the private equity professionals surveyed and 21.8% corporate development professionals indicating they are rethinking how they will access the public markets in 2022

OGA-2KA) in this loop region in an attempt to decouple this stalk-pHAT interaction does not alter hOGA activity, indicating that this interaction is not critical for regulating the activity of hOGA or substrate selection (Supplementary Fig