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This waning of efficacy is also observed for booster vaccination when Omicron is the dominant circulating variant, with Menegale et al

In CCH models, they attenuate astrocyte activation and improve cognition, showing synergy with STAT3 inhibitors (278)

Analysis of four mutants, viz E398A, E398D, E398R, and E398Q of BlGGT, suggested that the C-terminal of the large subunit was indeed critical for autoprocessing of BlGGT ( in vitro incubation