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Besides ddPCR-based techniques, the advent of novel high-throughput technologies such as sequencing approaches (e.g., next-generation sequencing and pyrosequencing) and microarray (e.g., Infinium HumanMethylation450k Bead Chip array and Infinium Human MethylationEPIC array by Illumina) has revolutionized the analysis of DNA methylation at single-nucleotide resolution [89, 90]

[DOI] [PMC free article] [PubMed] [Google Scholar] [37].Du J, Martin SM, Levine M, Wagner BA, Buettner GR, Wang SH, Taghiyev AF, Du C, Knudson CM, Cullen JJ, Mechanisms of ascorbate-induced cytotoxicity in pancreatic cancer, Clin

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Defective DNA Synthesis in Human Megaloblastic Bone Marrow: Effects of Hydroxy-B12 5-Deoxyadenosyl-B12 and Methyl-B12