does ghk-cu work systemically - Peptide for Collagen, Healing & Anti-Aging GHK-Cu Copper Peptide: What It

Elesclomol is widely recognized to induce copper overdose and cell death (139), by acting as a copper ion carrier with a hydrophilic pore in its centre, to which Cu2+ ions can bind easily, facilitating copper entry into cells, thus increasing the intracellular copper concentration (140), and this, in-turn increases ROS levels, triggering oxidative stress (141) and ultimately cell death

Ricard-Blum, S.) 6982 (Springer, 2020)

It is advisable to avoid layering multiple copper-containing products within the same regimen, as cumulative exposure may elevate copper levels beyond what is considered safe for topical use

10.1210/jcem-60-3-513 J

That difference is where clinical outcomes diverge from online experiment outcomes

Regulatory standards also require precise control of formulation composition, packaging materials, storage conditions, and degradation products