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Disentangling these effects requires controlled studies that have not yet been conducted

When adverse effects do occur following high-dose B12 administration, they are typically mild, transient, and often related to the route of administration rather than the vitamin itself

Those with diseases like Crohn's disease and celiac disease are also at risk, because these conditions hinder the body's ability to absorb B12

Vitamin B12 injections are primarily used to: Treat or prevent vitamin B12 deficiency Manage pernicious anemia Support patients with malabsorption disorders Aid those with dietary restrictions, such as vegans or vegetarians Offset vitamin loss due to medications like metformin or proton pump inhibitors (PPIs)

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Once youve done this for 2-3 months you can then recheck your homocysteine and MCV levels to check for improvement